Difference between revisions of "YNL031C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004976 YNL031C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HHT2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HHT2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIV:576051..575641 | |nowrap| Chr XIV:576051..575641 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004976 | ||
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| − | '''Description of | + | '''Description of YNL031C:''' One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation<ref name='S000073471'>Boa S, et al. (2003) Saccharomyces cerevisiae Set1p is a methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression. Yeast 20(9):827-35 {{SGDpaper|S000073471}} PMID 12845608</ref><ref name='S000073147'>Krogan NJ, et al. (2003) The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell 11(3):721-9 {{SGDpaper|S000073147}} PMID 12667454</ref><ref name='S000072594'>Thompson JS, et al. (2003) Identification of a Functional Domain Within the Essential Core of Histone H3 That Is Required for Telomeric and HM Silencing in Saccharomyces cerevisiae. Genetics 163(1):447-52 {{SGDpaper|S000072594}} PMID 12586729</ref><ref name='S000071381'>van Leeuwen F, et al. (2002) Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell 109(6):745-56 {{SGDpaper|S000071381}} PMID 12086673</ref><ref name='S000057267'>Smith MM and Andresson OS (1983) DNA sequences of yeast H3 and H4 histone genes from two non-allelic gene sets encode identical H3 and H4 proteins. J Mol Biol 169(3):663-90 {{SGDpaper|S000057267}} PMID 6355483</ref><ref name='S000053597'>Hsu JY, et al. (2000) Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102(3):279-91 {{SGDpaper|S000053597}} PMID 10975519</ref><ref name='S000046618'>Lo WS, et al. (2000) Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell 5(6):917-26 {{SGDpaper|S000046618}} PMID 10911986</ref><ref name='S000044144'>Zhang W, et al. (1998) Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase. EMBO J 17(11):3155-67 |
{{SGDpaper|S000044144}} PMID 9606197</ref> | {{SGDpaper|S000044144}} PMID 9606197</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL031C |
| Gene name | HHT2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:576051..575641 |
| Primary SGDID | S000004976 |
Description of YNL031C: One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation[1][2][3][4][5][6][7][8]
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References
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- ↑ Boa S, et al. (2003) Saccharomyces cerevisiae Set1p is a methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression. Yeast 20(9):827-35 SGD PMID 12845608
- ↑ Krogan NJ, et al. (2003) The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell 11(3):721-9 SGD PMID 12667454
- ↑ Thompson JS, et al. (2003) Identification of a Functional Domain Within the Essential Core of Histone H3 That Is Required for Telomeric and HM Silencing in Saccharomyces cerevisiae. Genetics 163(1):447-52 SGD PMID 12586729
- ↑ van Leeuwen F, et al. (2002) Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell 109(6):745-56 SGD PMID 12086673
- ↑ Smith MM and Andresson OS (1983) DNA sequences of yeast H3 and H4 histone genes from two non-allelic gene sets encode identical H3 and H4 proteins. J Mol Biol 169(3):663-90 SGD PMID 6355483
- ↑ Hsu JY, et al. (2000) Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102(3):279-91 SGD PMID 10975519
- ↑ Lo WS, et al. (2000) Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell 5(6):917-26 SGD PMID 10911986
- ↑ Zhang W, et al. (1998) Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase. EMBO J 17(11):3155-67 SGD PMID 9606197
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