Difference between revisions of "YGL248W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003217 YGL248W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PDE1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PDE1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VII:35653..36762 | |nowrap| Chr VII:35653..36762 | ||
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+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003217 | ||
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− | '''Description of | + | '''Description of YGL248W:''' Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation<ref name='S000055313'>Wera S, et al. (1997) Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast, Saccharomyces cerevisiae. FEBS Lett 420(2-3):147-50 {{SGDpaper|S000055313}} PMID 9459299</ref><ref name='S000055305'>Ma P, et al. (1999) The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling. Mol Biol Cell 10(1):91-104 {{SGDpaper|S000055305}} PMID 9880329</ref><ref name='S000044225'>Uno I, et al. (1983) Characterization of a cyclic nucleotide phosphodiesterase-deficient mutant in yeast. J Biol Chem 258(6):3539-42 {{SGDpaper|S000044225}} PMID 6300049</ref><ref name='S000042124'>Thevelein JM and de Winde JH (1999) Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 33(5):904-18 {{SGDpaper|S000042124}} PMID 10476026</ref><ref name='S000040124'>Nikawa J, et al. (1987) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Mol Cell Biol 7(10):3629-36 |
{{SGDpaper|S000040124}} PMID 2824992</ref> | {{SGDpaper|S000040124}} PMID 2824992</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> |
Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
Systematic name | YGL248W |
Gene name | PDE1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:35653..36762 |
Primary SGDID | S000003217 |
Description of YGL248W: Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation[1][2][3][4][5]
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Contents
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References
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- ↑ Wera S, et al. (1997) Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast, Saccharomyces cerevisiae. FEBS Lett 420(2-3):147-50 SGD PMID 9459299
- ↑ Ma P, et al. (1999) The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling. Mol Biol Cell 10(1):91-104 SGD PMID 9880329
- ↑ Uno I, et al. (1983) Characterization of a cyclic nucleotide phosphodiesterase-deficient mutant in yeast. J Biol Chem 258(6):3539-42 SGD PMID 6300049
- ↑ Thevelein JM and de Winde JH (1999) Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 33(5):904-18 SGD PMID 10476026
- ↑ Nikawa J, et al. (1987) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Mol Cell Biol 7(10):3629-36 SGD PMID 2824992
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