Difference between revisions of "YDR224C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002632 YDR224C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HTB1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HTB1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr IV:914708..914313 | |nowrap| Chr IV:914708..914313 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002632 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YDR224C:''' One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation <ref name='S000076743'>Yamashita K, et al. (2004) Rad6-Bre1-mediated histone H2B ubiquitylation modulates the formation of double-strand breaks during meiosis. Proc Natl Acad Sci U S A 101(31):11380-5 {{SGDpaper|S000076743}} PMID 15280549</ref><ref name='S000075526'>Kao CF, et al. (2004) Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B. Genes Dev 18(2):184-95 {{SGDpaper|S000075526}} PMID 14752010</ref><ref name='S000072664'>Hwang WW, et al. (2003) A conserved RING finger protein required for histone H2B monoubiquitination and cell size control. Mol Cell 11(1):261-6 {{SGDpaper|S000072664}} PMID 12535538</ref><ref name='S000070336'>Briggs SD, et al. (2002) Gene silencing: trans-histone regulatory pathway in chromatin. Nature 418(6897):498 {{SGDpaper|S000070336}} PMID 12152067</ref><ref name='S000070308'>Dover J, et al. (2002) Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem 277(32):28368-71 {{SGDpaper|S000070308}} PMID 12070136</ref><ref name='S000069711'>Martini EM, et al. (2002) A role for histone H2B during repair of UV-induced DNA damage in Saccharomyces cerevisiae. Genetics 160(4):1375-87 {{SGDpaper|S000069711}} PMID 11973294</ref><ref name='S000039551'>Robzyk K, et al. (2000) Rad6-dependent ubiquitination of histone H2B in yeast. Science 287(5452):501-4 |
{{SGDpaper|S000039551}} PMID 10642555</ref> | {{SGDpaper|S000039551}} PMID 10642555</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR224C |
| Gene name | HTB1 |
| Aliases | SPT12 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:914708..914313 |
| Primary SGDID | S000002632 |
Description of YDR224C: One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation [1][2][3][4][5][6][7]
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References
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- ↑ Yamashita K, et al. (2004) Rad6-Bre1-mediated histone H2B ubiquitylation modulates the formation of double-strand breaks during meiosis. Proc Natl Acad Sci U S A 101(31):11380-5 SGD PMID 15280549
- ↑ Kao CF, et al. (2004) Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B. Genes Dev 18(2):184-95 SGD PMID 14752010
- ↑ Hwang WW, et al. (2003) A conserved RING finger protein required for histone H2B monoubiquitination and cell size control. Mol Cell 11(1):261-6 SGD PMID 12535538
- ↑ Briggs SD, et al. (2002) Gene silencing: trans-histone regulatory pathway in chromatin. Nature 418(6897):498 SGD PMID 12152067
- ↑ Dover J, et al. (2002) Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem 277(32):28368-71 SGD PMID 12070136
- ↑ Martini EM, et al. (2002) A role for histone H2B during repair of UV-induced DNA damage in Saccharomyces cerevisiae. Genetics 160(4):1375-87 SGD PMID 11973294
- ↑ Robzyk K, et al. (2000) Rad6-dependent ubiquitination of histone H2B in yeast. Science 287(5452):501-4 SGD PMID 10642555
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