Difference between revisions of "YDR103W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002510 YDR103W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STE5 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STE5 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr IV:658347..661100 | |nowrap| Chr IV:658347..661100 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002510 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YDR103W:''' Pheromone-responsive scaffold protein; shuttles from the nucleus to the plasma membrane and assembles kinases Ste11p, Ste7p, and Fus3p into a specific signaling complex; active oligomeric form interacts with Ste4p-Ste18p complex<ref name='S000075489'>Wang Y and Elion EA (2003) Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components. Mol Biol Cell 14(6):2543-58 {{SGDpaper|S000075489}} PMID 12808050</ref><ref name='S000053549'>Kranz JE, et al. (1994) The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5. Genes Dev 8(3):313-27 {{SGDpaper|S000053549}} PMID 8314085</ref><ref name='S000050302'>Printen JA and Sprague GF Jr (1994) Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 138(3):609-19 {{SGDpaper|S000050302}} PMID 7851759</ref><ref name='S000048143'>Choi KY, et al. (1999) Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity. Mol Biol Cell 10(5):1553-68 |
{{SGDpaper|S000048143}} PMID 10233162</ref> | {{SGDpaper|S000048143}} PMID 10233162</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR103W |
| Gene name | STE5 |
| Aliases | HMD3, NUL3 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:658347..661100 |
| Primary SGDID | S000002510 |
Description of YDR103W: Pheromone-responsive scaffold protein; shuttles from the nucleus to the plasma membrane and assembles kinases Ste11p, Ste7p, and Fus3p into a specific signaling complex; active oligomeric form interacts with Ste4p-Ste18p complex[1][2][3][4]
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References
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- ↑ Wang Y and Elion EA (2003) Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components. Mol Biol Cell 14(6):2543-58 SGD PMID 12808050
- ↑ Kranz JE, et al. (1994) The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5. Genes Dev 8(3):313-27 SGD PMID 8314085
- ↑ Printen JA and Sprague GF Jr (1994) Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 138(3):609-19 SGD PMID 7851759
- ↑ Choi KY, et al. (1999) Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity. Mol Biol Cell 10(5):1553-68 SGD PMID 10233162
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