Difference between revisions of "YIL031W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001293 YIL031W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ULP2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ULP2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr IX:292632..295736 | |nowrap| Chr IX:292632..295736 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001293 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YIL031W:''' Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins, plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000070282'>Bachant J, et al. (2002) The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol Cell 9(6):1169-82 {{SGDpaper|S000070282}} PMID 12086615</ref><ref name='S000051720'>Li SJ and Hochstrasser M (2000) The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein. Mol Cell Biol 20(7):2367-77 |
{{SGDpaper|S000051720}} PMID 10713161</ref> | {{SGDpaper|S000051720}} PMID 10713161</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:45, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YIL031W |
| Gene name | ULP2 |
| Aliases | SMT4 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:292632..295736 |
| Primary SGDID | S000001293 |
Description of YIL031W: Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins, plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate[1][2][3]
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Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [4]
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References
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- ↑ 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Bachant J, et al. (2002) The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol Cell 9(6):1169-82 SGD PMID 12086615
- ↑ Li SJ and Hochstrasser M (2000) The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein. Mol Cell Biol 20(7):2367-77 SGD PMID 10713161
- ↑ submitted by Jeff Ubersax on 2004-01-27
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