Difference between revisions of "YOL149W"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 12:02, 21 February 2007
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| Systematic name | YOL149W |
| Gene name | DCP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:44937..45632 |
Description of YOL149W: Subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; enhances the activity of catalytic subunit Dcp2p; regulated by DEAD box protein Dhh1p[1][2][3][4][5]
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References
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- ↑ She M, et al. (2006) Crystal structure and functional analysis of Dcp2p from Schizosaccharomyces pombe. Nat Struct Mol Biol 13(1):63-70 SGD PMID 16341225
- ↑ Fischer N and Weis K (2002) The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1. EMBO J 21(11):2788-97 SGD PMID 12032091
- ↑ Vilela C, et al. (2000) The eukaryotic mRNA decapping protein Dcp1 interacts physically and functionally with the eIF4F translation initiation complex. EMBO J 19(16):4372-82 SGD PMID 10944120
- ↑ LaGrandeur TE and Parker R (1998) Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme. EMBO J 17(5):1487-96 SGD PMID 9482745
- ↑ Beelman CA, et al. (1996) An essential component of the decapping enzyme required for normal rates of mRNA turnover. Nature 382(6592):642-6 SGD PMID 8757137
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