Difference between revisions of "YNL329C"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 12:02, 21 February 2007
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| Systematic name | YNL329C |
| Gene name | PEX6 |
| Aliases | PAS8 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:22633..19541 |
Description of YNL329C: Peroxisomal membrane AAA-family ATPase peroxin required for peroxisome assembly, contains two 230 amino acid ATP-binding AAA cassettes, interacts with Pex1p[1][2]
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Community Commentary
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Protein Details
Other Protein Details
Other Topic: Homology
Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. [3] [4]
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References
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- ↑ Birschmann I, et al. (2005) Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p. FEBS J 272(1):47-58 SGD PMID 15634331
- ↑ Voorn-Brouwer T, et al. (1993) Sequence of the PAS8 gene, the product of which is essential for biogenesis of peroxisomes in Saccharomyces cerevisiae. Biochim Biophys Acta 1216(2):325-8 SGD PMID 8241279
- ↑ Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 SGD PMID 16556314
- ↑ submitted by Toni Gabaldon on 2006-04-12
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