Difference between revisions of "YLR006C"

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==Heat Shock==
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{| class="wikitable"
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|+ Wild Yeast Colonies at 50 degrees Celsius
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! Time (sec) !! Colonies !!
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| 0    || 24    ||
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| 15      || 14      ||
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| 45      || 8      ||
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| 75      || 9      ||
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| 105      || 10    ||
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| 135      || 15    ||
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==References==
 
==References==
 
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Revision as of 10:56, 2 May 2023

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Systematic name YLR006C
Gene name SSK1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:163893..161755
Primary SGDID S000003996


Description of YLR006C: Cytoplasmic response regulator; part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; required for mitophagy; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]




Heat Shock

Wild Yeast Colonies at 50 degrees Celsius
Time (sec) Colonies
0 24
15 14
45 8
75 9
105 10
135 15



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References

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  1. Mao K, et al. (2011) Two MAPK-signaling pathways are required for mitophagy in Saccharomyces cerevisiae. J Cell Biol 193(4):755-67 SGD PMID 21576396
  2. Posas F, et al. (1996) Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 two-component osmosensor. Cell 86(6):865-75 SGD PMID 8808622
  3. Sato N, et al. (2003) Phosphorelay-regulated degradation of the yeast Ssk1p response regulator by the ubiquitin-proteasome system. Mol Cell Biol 23(18):6662-71 SGD PMID 12944490
  4. 4.0 4.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415 Cite error: Invalid <ref> tag; name "S000074306" defined multiple times with different content
  5. submitted by Jeff Ubersax on 2004-01-29

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