Positions in yeast labs

Postdoctoral position on comparative transcriptomics in S. cerevisiae strains (posted 9th June 2022)

Contact: Mar Albà, ICREA Research Professor, Evolutionary Genomics Group, Hospital del Mar Medical Research Institute (IMIM) – Barcelona Biomedical Research Park (PRBB), Barcelona.

Description: Looking to recruit one highly motivated researcher at the postdoctoral level to perform research on comparative genomics, transcriptomics and translatomics with the goal to better understand the molecular basis of the evolution of new genes in yeast. The position is funded by an ERC Advanced Grant (NovoGenePop) and will have an initial duration of three years. The researcher will study transcriptome diversity in wild and domesticated populations of yeast. She/he will develop computational approaches to analyze a large amount of RNA-seq and Ribo-seq data from different S. cerevisiae strains and Saccharomyces species, characterize the transcriptomic diversity in different populations and develop methods to identify recently evolved genes. Mutations and selective signatures associated with de novo gene birth will be identified using genomics data from a large number of strains.

Requirements

• Research experience in comparative genomics and transcriptomics
• Expertise in at least one programming language
• Expertise in a programmatic statistics language (ideally R)
• Sound knowledge of population genetics and molecular evolution
• Excellent verbal and written communication skills in English

Representative publications

• Blevins, W.R., Ruiz-Orera, J., Messeguer, X., Blasco-Moreno, B., Villanueva-Cañas, J.L., Espinar, L., Díez, J., Carey, L.B., Albà, M.M. (2021). Uncovering de novo gene birth in yeast using deep transcriptomics. Nature Communications, vol. 12: 604.
• Blevins, W.R., Tavella, T., Moro, S.G., Blasco-Moreno, B., Closa-Mosquera, A., Diez, J., Carey, L.B., Albà, M.M. (2019) Extensive post-transcriptional buffering of gene expression in the response to severe oxidative stress in baker's yeast. Scientific Reports, vol. 9: 11005.

Post-doctoral position in S. cerevisiae research (posted 23 May 2022)

Truman lab, University of North Carolina at Charlotte, USA

Description: The Truman laboratory in the Department of Biological Sciences at UNC Charlotte employs a range of molecular technologies including mass spectrometry, CRISPR-genome engineering and high-throughput screening to study the role of post-translational modifications on Hsp70 (see: http://www.trumanlab.org). We are seeking a highly motivated postdoctoral researcher with experience working with budding yeast.

NIH Funding is available for several years, with the expectation that the candidate will work with Dr. Truman to apply for fellowships during this time. Ideal candidates will have graduated less than one year from their start date in the Truman lab. To apply please email Dr. Truman at atruman1@uncc.edu. Please include a cover letter, CV and any relevant publications.

About the Department of Biological Sciences: The Department of Biological Sciences (https://biology.charlotte.edu/) has set as its mission to advance the frontiers of knowledge through innovation and research in the biological sciences; to facilitate development of scientists in the guidance of our bachelors, masters and doctoral Biology students, and in the training of post-doctoral fellows; to contribute to local, national, and international scientific communities through collaborations and service activities that promote education and dissemination of information; to contribute to the community by collaborating with public, nonprofit, private, and industry partners in the Charlotte metropolitan area and the State of North Carolina.

The collaborative research environment at the UNC Charlotte offers an excellent opportunity for career development. The UNC Charlotte offers a complete benefits package and competitive salary. The Charlotte region provides wonderful environment to work and live.

Ideal Qualifications:

• Ph. D in biochemistry, molecular biology, cancer biology or related field.
• Experience with budding yeast including gene deletion, transformation etc.
• Experience with general molecular techniques such as Western Blotting, DNA cloning, coimmunoprecipitation.

Post-doctoral position in S. cerevisiae research (posted 13 December 2021)

De Wulf lab, University of Trento, Italy

Description: The De Wulf lab at the Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Italy, is looking for an outstanding, highly motivated post-doctoral scientist to study the biological activity of oncogenic kinetochore kinase Rio1. The research will aim to understand how this kinase regulates the chromatin at centromeres and pericentromeres to ensure correct levels of centromeric RNAs, required for faithful kinetochore recruitment. Candidates with expertise in yeast genetics, cell and molecular biology are encouraged to apply. Experience with live-cell fluorescence imaging is greatly appreciated. For publications related to the topic: Bock LJ et al (2012) Nature Cell Biology, Iacovella MG et al (2015) Nature Communications, Iacovella MG et al (2018) Nucleic Acids Research, Berto G et al (2019) Current Genetics. More details of currently submitted work and of the project itself will be provided upon request.

Position overview: The candidate should hold a recent PhD degree and a good publication record (at least one first-author publication in a reputable peer-reviewed journal). S/he must be motivated to excel in science, be curious, open-minded, and pro-active.

The lab is located in the city of Trento (150K inhabitants), near lakes and mountains, and lies close to Bolzano, Verona, and Venice.

Trento University is top 3-ranked in Italy, and CIBIO is the nr. 1 department of biology in Italy. State-of-the art equipment and facilities are available in our lab and in the department. Please visit our website for more information on our group, research interests and publications: http://www.cibio.unitn.it/510/chromosome-segregation-biology

How to apply: Please send a motivation letter, CV with publications, and the names and emails of 2-3 referees to Peter De Wulf (peter.dewulf@unitn.it). The University of Trento offers at first a 1-year contract, which can be renewed for up to 5 years. The salary is according to University of Trento pay scale.