Difference between revisions of "YMR224C"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 12:02, 21 February 2007
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| Systematic name | YMR224C |
| Gene name | MRE11 |
| Aliases | NGS1, RAD58, XRS4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:720652..718574 |
Description of YMR224C: Subunit of a complex with Rad50p and Xrs2p (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability, exhibits nuclease activity that appears to be required for RMX function; widely conserved[1][2][3]
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References
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- ↑ Lewis LK, et al. (2004) Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells. Genetics 166(4):1701-13 SGD PMID 15126391
- ↑ Moncalian G, et al. (2004) The rad50 signature motif: essential to ATP binding and biological function. J Mol Biol 335(4):937-51 SGD PMID 14698290
- ↑ D'Amours D and Jackson SP (2002) The Mre11 complex: at the crossroads of dna repair and checkpoint signalling. Nat Rev Mol Cell Biol 3(5):317-27 SGD PMID 11988766
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