Difference between revisions of "YBR069C"
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| − | '''Description of YBR069C:''' Amino acid | + | '''Description of YBR069C:''' Amino acid transporter for valine, leucine, isoleucine, and tyrosine; low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance; protein abundance increases in response to DNA replication stress<ref name='S000053575'>Bajmoczi M, et al. (1998) TAT1 encodes a low-affinity histidine transporter in Saccharomyces cerevisiae. Biochem Biophys Res Commun 243(1):205-9 {{SGDpaper|S000053575}} PMID 9473505</ref><ref name='S000041878'>Heitman J, et al. (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Mol Cell Biol 13(8):5010-9 {{SGDpaper|S000041878}} PMID 7687745</ref><ref name='S000043244'>Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 {{SGDpaper|S000043244}} PMID 10654085</ref><ref name='S000044967'>Schmidt A, et al. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Mol Cell Biol 14(10):6597-606 {{SGDpaper|S000044967}} PMID 7523855</ref><ref name='S000150401'>Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () {{SGDpaper|S000150401}} PMID 22842922</ref><ref name='S000073661'>Welsch CA, et al. (2003) Ubiquitin pathway proteins influence the mechanism of action of the novel immunosuppressive drug FTY720 in Saccharomyces cerevisiae. J Biol Chem 278(29):26976-82 |
{{SGDpaper|S000073661}} PMID 12709439</ref> | {{SGDpaper|S000073661}} PMID 12709439</ref> | ||
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Latest revision as of 14:05, 22 October 2012
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| Systematic name | YBR069C |
| Gene name | TAT1 |
| Aliases | TAP1, VAP1 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:378433..376574 |
| Primary SGDID | S000000273 |
Description of YBR069C: Amino acid transporter for valine, leucine, isoleucine, and tyrosine; low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance; protein abundance increases in response to DNA replication stress[1][2][3][4][5][6]
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References
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- Jump up ↑ Bajmoczi M, et al. (1998) TAT1 encodes a low-affinity histidine transporter in Saccharomyces cerevisiae. Biochem Biophys Res Commun 243(1):205-9 SGD PMID 9473505
- Jump up ↑ Heitman J, et al. (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Mol Cell Biol 13(8):5010-9 SGD PMID 7687745
- Jump up ↑ Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 SGD PMID 10654085
- Jump up ↑ Schmidt A, et al. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Mol Cell Biol 14(10):6597-606 SGD PMID 7523855
- Jump up ↑ Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () SGD PMID 22842922
- Jump up ↑ Welsch CA, et al. (2003) Ubiquitin pathway proteins influence the mechanism of action of the novel immunosuppressive drug FTY720 in Saccharomyces cerevisiae. J Biol Chem 278(29):26976-82 SGD PMID 12709439
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