Difference between revisions of "YGR097W"

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'''Description of YGR097W:''' Component of RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p; proposed to function in activation of the glycerol channel Fps1p; paralogous to Rgc1p<ref name='S000132427'>Beese SE, et al. (2009) Identification of positive regulators of the yeast fps1 glycerol channel. PLoS Genet 5(11):e1000738 {{SGDpaper|S000132427}} PMID 19956799</ref><ref name='S000074242'>Cohen TJ, et al. (2003) Ask10p mediates the oxidative stress-induced destruction of the Saccharomyces cerevisiae C-type cyclin Ume3p/Srb11p. Eukaryot Cell 2(5):962-70
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'''Description of YGR097W:''' Component of RNA polymerase II holoenzyme; phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p; proposed to function in activation of the glycerol channel Fps1p; ASK10 has a paralog, RGC1, that arose from the whole genome duplication<ref name='S000132427'>Beese SE, et al. (2009) Identification of positive regulators of the yeast fps1 glycerol channel. PLoS Genet 5(11):e1000738 {{SGDpaper|S000132427}} PMID 19956799</ref><ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000074242'>Cohen TJ, et al. (2003) Ask10p mediates the oxidative stress-induced destruction of the Saccharomyces cerevisiae C-type cyclin Ume3p/Srb11p. Eukaryot Cell 2(5):962-70
 
  {{SGDpaper|S000074242}} PMID 14555478</ref>
 
  {{SGDpaper|S000074242}} PMID 14555478</ref>
 
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Latest revision as of 13:05, 20 October 2012

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Systematic name YGR097W
Gene name ASK10
Aliases RGC2
Feature type ORF, Verified
Coordinates Chr VII:678695..682135
Primary SGDID S000003329


Description of YGR097W: Component of RNA polymerase II holoenzyme; phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p; proposed to function in activation of the glycerol channel Fps1p; ASK10 has a paralog, RGC1, that arose from the whole genome duplication[1][2][3]




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References

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  1. Beese SE, et al. (2009) Identification of positive regulators of the yeast fps1 glycerol channel. PLoS Genet 5(11):e1000738 SGD PMID 19956799
  2. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  3. Cohen TJ, et al. (2003) Ask10p mediates the oxidative stress-induced destruction of the Saccharomyces cerevisiae C-type cyclin Ume3p/Srb11p. Eukaryot Cell 2(5):962-70 SGD PMID 14555478

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