Difference between revisions of "YAR015W"
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| − | '''Description of YAR015W:''' N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine<ref name='S000070200'>Jones EW and Fink GR (1982) Regulation of amino acid and nucleotide biosynthesis in yeast. Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000070200}} PMID </ref><ref name='S000039345'>Myasnikov AN, et al. (1991) The Saccharomyces cerevisiae ADE1 gene: structure, overexpression and possible regulation by general amino acid control. Gene 109(1):143-7 | + | '''Description of YAR015W:''' N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine; protein abundance increases in response to DNA replication stress<ref name='S000070200'>Jones EW and Fink GR (1982) Regulation of amino acid and nucleotide biosynthesis in yeast. Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000070200}} PMID </ref><ref name='S000039345'>Myasnikov AN, et al. (1991) The Saccharomyces cerevisiae ADE1 gene: structure, overexpression and possible regulation by general amino acid control. Gene 109(1):143-7 {{SGDpaper|S000039345}} PMID 1756975</ref><ref name='S000150401'>Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () |
| − | {{SGDpaper| | + | {{SGDpaper|S000150401}} PMID 22842922</ref> |
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Latest revision as of 13:05, 18 October 2012
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| Systematic name | YAR015W |
| Gene name | ADE1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr I:169375..170295 |
| Primary SGDID | S000000070 |
Description of YAR015W: N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine; protein abundance increases in response to DNA replication stress[1][2][3]
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References
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- ↑ Jones EW and Fink GR (1982) Regulation of amino acid and nucleotide biosynthesis in yeast. Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
- ↑ Myasnikov AN, et al. (1991) The Saccharomyces cerevisiae ADE1 gene: structure, overexpression and possible regulation by general amino acid control. Gene 109(1):143-7 SGD PMID 1756975
- ↑ Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () SGD PMID 22842922
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