Difference between revisions of "YKL195W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YKL195W
Gene name MIA40
Aliases FMP15, TIM40
Feature type ORF, Verified
Coordinates Chr XI:75826..77037


Description of YKL195W: Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins[1][2][3]




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References

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  1. Mesecke N, et al. (2005) A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 121(7):1059-69 SGD PMID 15989955
  2. Terziyska N, et al. (2005) Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett 579(1):179-84 SGD PMID 15620710
  3. Chacinska A, et al. (2004) Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J 23(19):3735-46 SGD PMID 15359280

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