Difference between revisions of "YGR214W"

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'''Description of YGR214W:''' Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal<ref name='S000045335'>Demianova M, et al. (1996) Yeast proteins related to the p40/laminin receptor precursor are essential components of the 40 S ribosomal subunit. J Biol Chem 271(19):11383-91 {{SGDpaper|S000045335}} PMID 8626693</ref><ref name='S000044568'>Ford CL, et al. (1999) Yeast proteins related to the p40/laminin receptor precursor are required for 20S ribosomal RNA processing and the maturation of 40S ribosomal subunits. Cancer Res 59(3):704-10 {{SGDpaper|S000044568}} PMID 9973221</ref><ref name='S000074367'>Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90
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'''Description of YGR214W:''' Protein component of the small (40S) ribosomal subunit; RPS0A has a paralog, RPS0B, that arose from the whole genome duplication; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal; homologous to human ribosomal protein SA and bacterial S2<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000045335'>Demianova M, et al. (1996) Yeast proteins related to the p40/laminin receptor precursor are essential components of the 40 S ribosomal subunit. J Biol Chem 271(19):11383-91 {{SGDpaper|S000045335}} PMID 8626693</ref><ref name='S000044568'>Ford CL, et al. (1999) Yeast proteins related to the p40/laminin receptor precursor are required for 20S ribosomal RNA processing and the maturation of 40S ribosomal subunits. Cancer Res 59(3):704-10 {{SGDpaper|S000044568}} PMID 9973221</ref><ref name='S000150523'>Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () {{SGDpaper|S000150523}} PMID 22884264</ref><ref name='S000074367'>Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90
 
  {{SGDpaper|S000074367}} PMID 12490706</ref>
 
  {{SGDpaper|S000074367}} PMID 12490706</ref>
 
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Revision as of 13:05, 15 September 2012

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Systematic name YGR214W
Gene name RPS0A
Aliases NAB1, NAB1A, YST1
Feature type ORF, Verified
Coordinates Chr VII:920575..921788
Primary SGDID S000003446


Description of YGR214W: Protein component of the small (40S) ribosomal subunit; RPS0A has a paralog, RPS0B, that arose from the whole genome duplication; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal; homologous to human ribosomal protein SA and bacterial S2[1][2][3][4][5]




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References

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  1. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. Demianova M, et al. (1996) Yeast proteins related to the p40/laminin receptor precursor are essential components of the 40 S ribosomal subunit. J Biol Chem 271(19):11383-91 SGD PMID 8626693
  3. Ford CL, et al. (1999) Yeast proteins related to the p40/laminin receptor precursor are required for 20S ribosomal RNA processing and the maturation of 40S ribosomal subunits. Cancer Res 59(3):704-10 SGD PMID 9973221
  4. Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () SGD PMID 22884264
  5. Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 SGD PMID 12490706

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