Difference between revisions of "YMR153W"

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'''Description of YMR153W:''' Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p, involved in activation of the spindle checkpoint mediated by the Mad1p-Mad2p complex<ref name='S000071853'>Iouk T, et al. (2002) The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. J Cell Biol 159(5):807-19 {{SGDpaper|S000071853}} PMID 12473689</ref><ref name='S000071714'>Lusk CP, et al. (2002) Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes. J Cell Biol 159(2):267-78
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'''Description of YMR153W:''' FG-nucleoporin component of central core of the nuclear pore complex (NPC); also part of the NPC nuclear basket; contributes directly to nucleocytoplasmic transport; involved in regulation of transcription and mitosis<ref name='S000062434'>Fahrenkrog B, et al. (2000) The yeast nucleoporin Nup53p specifically interacts with Nic96p and is directly involved in nuclear protein import. Mol Biol Cell 11(11):3885-96 {{SGDpaper|S000062434}} PMID 11071914</ref><ref name='S000071853'>Iouk T, et al. (2002) The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. J Cell Biol 159(5):807-19 {{SGDpaper|S000071853}} PMID 12473689</ref><ref name='S000071714'>Lusk CP, et al. (2002) Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes. J Cell Biol 159(2):267-78 {{SGDpaper|S000071714}} PMID 12403813</ref><ref name='S000074647'>Makhnevych T, et al. (2003) Cell cycle regulated transport controlled by alterations in the nuclear pore complex. Cell 115(7):813-23 {{SGDpaper|S000074647}} PMID 14697200</ref><ref name='S000055428'>Marelli M, et al. (1998) Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p. J Cell Biol 143(7):1813-30 {{SGDpaper|S000055428}} PMID 9864357</ref><ref name='S000081345'>Menon BB, et al. (2005) Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci U S A 102(16):5749-54 {{SGDpaper|S000081345}} PMID 15817685</ref><ref name='S000122438'>Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96
  {{SGDpaper|S000071714}} PMID 12403813</ref>
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  {{SGDpaper|S000122438}} PMID 17418788</ref>
 
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Latest revision as of 13:05, 19 June 2012

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Systematic name YMR153W
Gene name NUP53
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:564435..565862
Primary SGDID S000004762


Description of YMR153W: FG-nucleoporin component of central core of the nuclear pore complex (NPC); also part of the NPC nuclear basket; contributes directly to nucleocytoplasmic transport; involved in regulation of transcription and mitosis[1][2][3][4][5][6][7]




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References

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  1. Fahrenkrog B, et al. (2000) The yeast nucleoporin Nup53p specifically interacts with Nic96p and is directly involved in nuclear protein import. Mol Biol Cell 11(11):3885-96 SGD PMID 11071914
  2. Iouk T, et al. (2002) The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. J Cell Biol 159(5):807-19 SGD PMID 12473689
  3. Lusk CP, et al. (2002) Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes. J Cell Biol 159(2):267-78 SGD PMID 12403813
  4. Makhnevych T, et al. (2003) Cell cycle regulated transport controlled by alterations in the nuclear pore complex. Cell 115(7):813-23 SGD PMID 14697200
  5. Marelli M, et al. (1998) Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p. J Cell Biol 143(7):1813-30 SGD PMID 9864357
  6. Menon BB, et al. (2005) Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci U S A 102(16):5749-54 SGD PMID 15817685
  7. Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 SGD PMID 17418788

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