Difference between revisions of "YGL062W"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 12:02, 21 February 2007
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| Systematic name | YGL062W |
| Gene name | PYC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:385199..388735 |
Description of YGL062W: Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis[1][2][3]
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References
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- ↑ Foury F (1997) Human genetic diseases: a cross-talk between man and yeast. Gene 195(1):1-10 SGD PMID 9300813
- ↑ Brewster NK, et al. (1994) Regulation of pyruvate carboxylase isozyme (PYC1, PYC2) gene expression in Saccharomyces cerevisiae during fermentative and nonfermentative growth. Arch Biochem Biophys 311(1):62-71 SGD PMID 8185321
- ↑ Walker ME, et al. (1991) Yeast pyruvate carboxylase: identification of two genes encoding isoenzymes. Biochem Biophys Res Commun 176(3):1210-7 SGD PMID 2039506
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