Difference between revisions of "YPR111W"
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| − | '''Description of YPR111W:''' Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis<ref name='S000075899'>Hwa Lim H, et al. (2003) Inactivation of mitotic kinase triggers translocation of MEN components to mother-daughter neck in yeast. Mol Biol Cell 14(11):4734-43 {{SGDpaper|S000075899}} PMID 12937277</ref><ref name='S000059953'>Menssen R, et al. (2001) Asymmetric spindle pole localization of yeast Cdc15 kinase links mitotic exit and cytokinesis. Curr Biol 11(5):345-50 {{SGDpaper|S000059953}} PMID 11267871</ref><ref name='S000048013'>Toyn JH and Johnston LH (1994) The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition. EMBO J 13(5):1103-13 | + | '''Description of YPR111W:''' Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs<ref name='S000075899'>Hwa Lim H, et al. (2003) Inactivation of mitotic kinase triggers translocation of MEN components to mother-daughter neck in yeast. Mol Biol Cell 14(11):4734-43 {{SGDpaper|S000075899}} PMID 12937277</ref><ref name='S000059953'>Menssen R, et al. (2001) Asymmetric spindle pole localization of yeast Cdc15 kinase links mitotic exit and cytokinesis. Curr Biol 11(5):345-50 {{SGDpaper|S000059953}} PMID 11267871</ref><ref name='S000048013'>Toyn JH and Johnston LH (1994) The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition. EMBO J 13(5):1103-13 {{SGDpaper|S000048013}} PMID 8131744</ref><ref name='S000147928'>Trcek T, et al. (2011) Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell 147(7):1484-97 |
| − | {{SGDpaper| | + | {{SGDpaper|S000147928}} PMID 22196726</ref> |
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Latest revision as of 13:05, 14 May 2012
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| Systematic name | YPR111W |
| Gene name | DBF20 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:747306..749000 |
| Primary SGDID | S000006315 |
Description of YPR111W: Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
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- ↑ Hwa Lim H, et al. (2003) Inactivation of mitotic kinase triggers translocation of MEN components to mother-daughter neck in yeast. Mol Biol Cell 14(11):4734-43 SGD PMID 12937277
- ↑ Menssen R, et al. (2001) Asymmetric spindle pole localization of yeast Cdc15 kinase links mitotic exit and cytokinesis. Curr Biol 11(5):345-50 SGD PMID 11267871
- ↑ Toyn JH and Johnston LH (1994) The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition. EMBO J 13(5):1103-13 SGD PMID 8131744
- ↑ Trcek T, et al. (2011) Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell 147(7):1484-97 SGD PMID 22196726
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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