Difference between revisions of "YKR087C"
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| − | '''Description of YKR087C:''' Metalloendopeptidase of the mitochondrial inner membrane | + | '''Description of YKR087C:''' Metalloendopeptidase of the mitochondrial inner membrane; involved in turnover of membrane-embedded proteins; mediates degradation of Cox1p in coa2 mutant cells; member of a family of predicted membrane-bound metallopeptidases in prokaryotes and higher eukaryotes<ref name='S000074704'>Kaser M, et al. (2003) Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease. J Biol Chem 278(47):46414-23 {{SGDpaper|S000074704}} PMID 12963738</ref><ref name='S000149336'>Khalimonchuk O, et al. (2012) Selective Oma1 protease-mediated proteolysis of Cox1 subunit of cytochrome oxidase in assembly mutants. J Biol Chem 287(10):7289-300 |
| − | {{SGDpaper| | + | {{SGDpaper|S000149336}} PMID 22219186</ref> |
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Latest revision as of 13:05, 7 May 2012
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| Systematic name | YKR087C |
| Gene name | OMA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:604232..603195 |
| Primary SGDID | S000001795 |
Description of YKR087C: Metalloendopeptidase of the mitochondrial inner membrane; involved in turnover of membrane-embedded proteins; mediates degradation of Cox1p in coa2 mutant cells; member of a family of predicted membrane-bound metallopeptidases in prokaryotes and higher eukaryotes[1][2]
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References
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- ↑ Kaser M, et al. (2003) Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease. J Biol Chem 278(47):46414-23 SGD PMID 12963738
- ↑ Khalimonchuk O, et al. (2012) Selective Oma1 protease-mediated proteolysis of Cox1 subunit of cytochrome oxidase in assembly mutants. J Biol Chem 287(10):7289-300 SGD PMID 22219186
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