Difference between revisions of "YER019W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YER019W
Gene name ISC1
Aliases
Feature type ORF, Verified
Coordinates Chr V:192796..194229


Description of YER019W: Inositol phosphosphingolipid phospholipase C, hydrolyzes inositolphosphosphingolipids, activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol, mediates Na+ and Li+ halotolerance, contains a P loop-like domain[1][2][3]




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References

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  1. Okamoto Y, et al. (2002) Structural requirements for selective binding of ISC1 to anionic phospholipids. J Biol Chem 277(48):46470-7 SGD PMID 12244059
  2. Betz C, et al. (2002) ISC1-encoded inositol phosphosphingolipid phospholipase C is involved in Na+/Li+ halotolerance of Saccharomyces cerevisiae. Eur J Biochem 269(16):4033-9 SGD PMID 12180980
  3. Sawai H, et al. (2000) Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae. J Biol Chem 275(50):39793-8 SGD PMID 11006294

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