Difference between revisions of "YMR312W"
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| − | '''Description of YMR312W:''' Subunit of Elongator | + | '''Description of YMR312W:''' Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity<ref name='S000119100'>Esberg A, et al. (2006) Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell 24(1):139-48 {{SGDpaper|S000119100}} PMID 17018299</ref><ref name='S000072244'>Frohloff F, et al. (2003) Subunit communications crucial for the functional integrity of the yeast RNA polymerase II elongator (gamma-toxin target (TOT)) complex. J Biol Chem 278(2):956-61 {{SGDpaper|S000072244}} PMID 12424236</ref><ref name='S000148498'>Glatt S, et al. (2012) The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase.LID - 10.1038/nsmb.2234 [doi] Nat Struct Mol Biol () {{SGDpaper|S000148498}} PMID 22343726</ref><ref name='S000069595'>Winkler GS, et al. (2002) Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo. Proc Natl Acad Sci U S A 99(6):3517-22 |
{{SGDpaper|S000069595}} PMID 11904415</ref> | {{SGDpaper|S000069595}} PMID 11904415</ref> | ||
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Latest revision as of 14:05, 7 March 2012
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| Systematic name | YMR312W |
| Gene name | ELP6 |
| Aliases | HAP3, KTI4, TOT6 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:898405..899226 |
| Primary SGDID | S000004929 |
Description of YMR312W: Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity[1][2][3][4]
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References
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- ↑ Esberg A, et al. (2006) Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell 24(1):139-48 SGD PMID 17018299
- ↑ Frohloff F, et al. (2003) Subunit communications crucial for the functional integrity of the yeast RNA polymerase II elongator (gamma-toxin target (TOT)) complex. J Biol Chem 278(2):956-61 SGD PMID 12424236
- ↑ Glatt S, et al. (2012) The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase.LID - 10.1038/nsmb.2234 [doi] Nat Struct Mol Biol () SGD PMID 22343726
- ↑ Winkler GS, et al. (2002) Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo. Proc Natl Acad Sci U S A 99(6):3517-22 SGD PMID 11904415
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