Difference between revisions of "YOR322C"
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| − | '''Description of YOR322C:''' Protein involved in regulating the endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its target; | + | '''Description of YOR322C:''' Protein involved in regulating the endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its target; inhibited by Npr1p-mediated phosphorylation at N-terminal amino acids, which controls translocation between the cytosol and the plasma membrane; null mutant has reduced affinity for alcian blue dye<ref name='S000082235'>Corbacho I, et al. (2005) A genome-wide screen for Saccharomyces cerevisiae nonessential genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccharides. Fungal Genet Biol 42(9):773-90 {{SGDpaper|S000082235}} PMID 15993632</ref><ref name='S000128206'>Lin CH, et al. (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25 {{SGDpaper|S000128206}} PMID 18976803</ref><ref name='S000148186'>MacGurn JA, et al. (2011) TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor. Cell 147(5):1104-17 |
| − | {{SGDpaper| | + | {{SGDpaper|S000148186}} PMID 22118465</ref> |
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Revision as of 13:05, 24 February 2012
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| Systematic name | YOR322C |
| Gene name | LDB19 |
| Aliases | ART1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:921062..918606 |
| Primary SGDID | S000005849 |
Description of YOR322C: Protein involved in regulating the endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its target; inhibited by Npr1p-mediated phosphorylation at N-terminal amino acids, which controls translocation between the cytosol and the plasma membrane; null mutant has reduced affinity for alcian blue dye[1][2][3]
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References
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- ↑ Corbacho I, et al. (2005) A genome-wide screen for Saccharomyces cerevisiae nonessential genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccharides. Fungal Genet Biol 42(9):773-90 SGD PMID 15993632
- ↑ Lin CH, et al. (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25 SGD PMID 18976803
- ↑ MacGurn JA, et al. (2011) TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor. Cell 147(5):1104-17 SGD PMID 22118465
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