Difference between revisions of "YNL191W"
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| − | '''Description of YNL191W:''' | + | '''Description of YNL191W:''' Component of glutamine amidotransferase (GATase II); forms a complex with Dug2p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)<ref name='S000120080'>Ganguli D, et al. (2007) The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae. Genetics 175(3):1137-51 {{SGDpaper|S000120080}} PMID 17179087</ref><ref name='S000148140'>Kaur H, et al. (2012) Glutathione degradation by the alternative pathway (DUG pahway) in Saccharomyces cerevisiae is initiated by the (Dug2p-Dug3p)2 complex, a novel GATase enzyme acting on glutathione. J Biol Chem () |
| − | {{SGDpaper| | + | {{SGDpaper|S000148140}} PMID 22277648</ref> |
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Latest revision as of 13:05, 9 February 2012
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| Systematic name | YNL191W |
| Gene name | DUG3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:280432..281505 |
| Primary SGDID | S000005135 |
Description of YNL191W: Component of glutamine amidotransferase (GATase II); forms a complex with Dug2p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)[1][2]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in sulfur limited chemostat cultures versus sulfur excess. [3] [4]
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References
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- ↑ Ganguli D, et al. (2007) The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae. Genetics 175(3):1137-51 SGD PMID 17179087
- ↑ Kaur H, et al. (2012) Glutathione degradation by the alternative pathway (DUG pahway) in Saccharomyces cerevisiae is initiated by the (Dug2p-Dug3p)2 complex, a novel GATase enzyme acting on glutathione. J Biol Chem () SGD PMID 22277648
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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