Difference between revisions of "YOL115W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005475 YOL115W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005475 YOL115W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PAP2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PAP2 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YOL115W
Gene name PAP2
Aliases TRF4
Feature type ORF, Verified
Coordinates Chr XV:101475..103229
Primary SGDID S000005475


Description of YOL115W: Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Trf5p[1][2][3][4]




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References

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  1. Gellon L, et al. (2008) Intrinsic 5'-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair. DNA Repair (Amst) 7(2):187-98 SGD PMID 17983848
  2. LaCava J, et al. (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 121(5):713-24 SGD PMID 15935758
  3. Vanacova S, et al. (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol 3(6):e189 SGD PMID 15828860
  4. Wyers F, et al. (2005) Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell 121(5):725-37 SGD PMID 15935759

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