Difference between revisions of "YOL110W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005470 YOL110W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005470 YOL110W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SHR5 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SHR5 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YOL110W
Gene name SHR5
Aliases ERF4
Feature type ORF, Verified
Coordinates Chr XV:109176..109889
Primary SGDID S000005470


Description of YOL110W: Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization[1][2][3]




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References

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  1. Dong X, et al. (2003) Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae. Mol Cell Biol 23(18):6574-84 SGD PMID 12944483
  2. Roth AF, et al. (2006) Global analysis of protein palmitoylation in yeast. Cell 125(5):1003-13 SGD PMID 16751107
  3. Zhao L, et al. (2002) Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins. J Biol Chem 277(51):49352-9 SGD PMID 12379641

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