Difference between revisions of "YGR232W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003464 YGR232W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003464 YGR232W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NAS6 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NAS6 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YGR232W
Gene name NAS6
Aliases
Feature type ORF, Verified
Coordinates Chr VII:953960..954646
Primary SGDID S000003464


Description of YGR232W: Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6[1][2][3][4][5]




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References

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  1. Funakoshi M, et al. (2009) Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base. Cell 137(5):887-99 SGD PMID 19446322
  2. Hori T, et al. (1998) cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome. Gene 216(1):113-22 SGD PMID 9714768
  3. Padmanabhan B, et al. (2004) Crystal structure of the homolog of the oncoprotein gankyrin, an interactor of Rb and CDK4/6. J Biol Chem 279(2):1546-52 SGD PMID 14583612
  4. Roelofs J, et al. (2009) Chaperone-mediated pathway of proteasome regulatory particle assembly. Nature 459(7248):861-5 SGD PMID 19412159
  5. Saeki Y, et al. (2009) Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle. Cell 137(5):900-13 SGD PMID 19446323

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