Difference between revisions of "YDL142C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002301 YDL142C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002301 YDL142C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CRD1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CRD1 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YDL142C
Gene name CRD1
Aliases CLS1
Feature type ORF, Verified
Coordinates Chr IV:202570..201719
Primary SGDID S000002301


Description of YDL142C: Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis[1][2][3][4][5]




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References

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  1. Chang SC, et al. (1998) Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae. J Biol Chem 273(24):14933-41 SGD PMID 9614098
  2. Chen S, et al. (2008) Cardiolipin mediates cross-talk between mitochondria and the vacuole. Mol Biol Cell 19(12):5047-58 SGD PMID 18799619
  3. Jiang F, et al. (1999) Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development. Mol Microbiol 31(1):373-9 SGD PMID 9987137
  4. Jiang F, et al. (2000) Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J Biol Chem 275(29):22387-94 SGD PMID 10777514
  5. Zhang M, et al. (2003) Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures. J Biol Chem 278(37):35204-10 SGD PMID 12840009

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