Difference between revisions of "YHR007C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001049 YHR007C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ERG11 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ERG11 '' | ||
Latest revision as of 06:45, 23 January 2012
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| Systematic name | YHR007C |
| Gene name | ERG11 |
| Aliases | CYP51 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:121683..120091 |
| Primary SGDID | S000001049 |
Description of YHR007C: Lanosterol 14-alpha-demethylase; catalyzes the C-14 demethylation of lanosterol to form 4,4-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p[1][2][3][4][5][6]
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Community Commentary
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NCP1 encodes the reductase that acts on Erg11, lanosterol demethylase
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References
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- ↑ Kalb VF, et al. (1987) Primary structure of the P450 lanosterol demethylase gene from Saccharomyces cerevisiae. DNA 6(6):529-37 SGD PMID 3322742
- ↑ Paltauf F, et al. (1992) Regulation and compartmentalization of lipid synthesis in yeast. Pp. 415-500 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
- ↑ Parks LW, et al. (1995) Biochemical and physiological effects of sterol alterations in yeast--a review. Lipids 30(3):227-30 SGD PMID 7791530
- ↑ Truan G, et al. (1994) Cloning and characterization of a yeast cytochrome b5-encoding gene which suppresses ketoconazole hypersensitivity in a NADPH-P-450 reductase-deficient strain. Gene 142(1):123-7 SGD PMID 8181746
- ↑ Turi TG and Loper JC (1992) Multiple regulatory elements control expression of the gene encoding the Saccharomyces cerevisiae cytochrome P450, lanosterol 14 alpha-demethylase (ERG11). J Biol Chem 267(3):2046-56 SGD PMID 1730736
- ↑ Yoshida Y and Aoyama Y (1987) Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes. Biochem Pharmacol 36(2):229-35 SGD PMID 3545213
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References
See Help:References on how to add references
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
