Difference between revisions of "YER055C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000857 YER055C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HIS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HIS1 '' | ||
Latest revision as of 07:45, 23 January 2012
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| Systematic name | YER055C |
| Gene name | HIS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:265785..264892 |
| Primary SGDID | S000000857 |
Description of YER055C: ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control[1][2][3]
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Contents
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References
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- Jump up ↑ Alifano P, et al. (1996) Histidine biosynthetic pathway and genes: structure, regulation, and evolution. Microbiol Rev 60(1):44-69 SGD PMID 8852895
- Jump up ↑ Hinnebusch AG and Fink GR (1983) Repeated DNA sequences upstream from HIS1 also occur at several other co-regulated genes in Saccharomyces cerevisiae. J Biol Chem 258(8):5238-47 SGD PMID 6300123
- Jump up ↑ Pearce DA and Sherman F (1999) Toxicity of copper, cobalt, and nickel salts is dependent on histidine metabolism in the yeast Saccharomyces cerevisiae. J Bacteriol 181(16):4774-9 SGD PMID 10438744
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