Difference between revisions of "YJR057W"
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− | '''Description of YJR057W:''' Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p<ref name='S000039605'>Abaigar LT, et al. (1992) Functional and structural conservation of Schizosaccharomyces pombe dTMP kinase gene. Biochim Biophys Acta 1132(2):222-4 {{SGDpaper|S000039605}} PMID 1327149</ref><ref name='S000049877'>Jong AY and Campbell JL (1984) Characterization of Saccharomyces cerevisiae thymidylate kinase, the CDC8 gene product. General properties, kinetic analysis, and subcellular localization. J Biol Chem 259(23):14394-8 | + | '''Description of YJR057W:''' Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p<ref name='S000039605'>Abaigar LT, et al. (1992) Functional and structural conservation of Schizosaccharomyces pombe dTMP kinase gene. Biochim Biophys Acta 1132(2):222-4 {{SGDpaper|S000039605}} PMID 1327149</ref><ref name='S000049877'>Jong AY and Campbell JL (1984) Characterization of Saccharomyces cerevisiae thymidylate kinase, the CDC8 gene product. General properties, kinetic analysis, and subcellular localization. J Biol Chem 259(23):14394-8 {{SGDpaper|S000049877}} PMID 6094555</ref><ref name='S000053290'>Jong AY, et al. (1984) The CDC8 gene of yeast encodes thymidylate kinase. J Biol Chem 259(17):11052-9 {{SGDpaper|S000053290}} PMID 6088527</ref><ref name='S000042433'>Sclafani RA and Fangman WL (1984) Yeast gene CDC8 encodes thymidylate kinase and is complemented by herpes thymidine kinase gene TK. Proc Natl Acad Sci U S A 81(18):5821-5 |
− | {{SGDpaper| | + | {{SGDpaper|S000042433}} PMID 6091111</ref> |
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Revision as of 14:05, 23 June 2011
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Systematic name | YJR057W |
Gene name | CDC8 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr X:544062..544712 |
Primary SGDID | S000003818 |
Description of YJR057W: Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p[1][2][3][4]
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References
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- ↑ Abaigar LT, et al. (1992) Functional and structural conservation of Schizosaccharomyces pombe dTMP kinase gene. Biochim Biophys Acta 1132(2):222-4 SGD PMID 1327149
- ↑ Jong AY and Campbell JL (1984) Characterization of Saccharomyces cerevisiae thymidylate kinase, the CDC8 gene product. General properties, kinetic analysis, and subcellular localization. J Biol Chem 259(23):14394-8 SGD PMID 6094555
- ↑ Jong AY, et al. (1984) The CDC8 gene of yeast encodes thymidylate kinase. J Biol Chem 259(17):11052-9 SGD PMID 6088527
- ↑ Sclafani RA and Fangman WL (1984) Yeast gene CDC8 encodes thymidylate kinase and is complemented by herpes thymidine kinase gene TK. Proc Natl Acad Sci U S A 81(18):5821-5 SGD PMID 6091111
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