Difference between revisions of "YLR113W"
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− | '''Description of YLR113W:''' Mitogen-activated protein kinase involved in osmoregulation via three independent osmosensors; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p<ref name='S000068841'>Alepuz PM, et al. (2003) Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II. EMBO J 22(10):2433-42 {{SGDpaper|S000068841}} PMID 12743037</ref><ref name='S000046190'>Brewster JL, et al. (1993) An osmosensing signal transduction pathway in yeast. Science 259(5102):1760-3 {{SGDpaper|S000046190}} PMID 7681220</ref><ref name='S000050031'>Mattison CP and Ota IM (2000) Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast. Genes Dev 14(10):1229-35 {{SGDpaper|S000050031}} PMID 10817757</ref><ref name='S000070226'>O'Rourke SM and Herskowitz I (2002) A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel with the Sho1 branch. Mol Cell Biol 22(13):4739-49 | + | '''Description of YLR113W:''' Mitogen-activated protein kinase involved in osmoregulation; acts via three independent osmosensors; mitophagy-specific regulator; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p<ref name='S000068841'>Alepuz PM, et al. (2003) Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II. EMBO J 22(10):2433-42 {{SGDpaper|S000068841}} PMID 12743037</ref><ref name='S000046190'>Brewster JL, et al. (1993) An osmosensing signal transduction pathway in yeast. Science 259(5102):1760-3 {{SGDpaper|S000046190}} PMID 7681220</ref><ref name='S000145416'>Mao K, et al. (2011) Two MAPK-signaling pathways are required for mitophagy in Saccharomyces cerevisiae. J Cell Biol 193(4):755-67 {{SGDpaper|S000145416}} PMID 21576396</ref><ref name='S000050031'>Mattison CP and Ota IM (2000) Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast. Genes Dev 14(10):1229-35 {{SGDpaper|S000050031}} PMID 10817757</ref><ref name='S000070226'>O'Rourke SM and Herskowitz I (2002) A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel with the Sho1 branch. Mol Cell Biol 22(13):4739-49 |
{{SGDpaper|S000070226}} PMID 12052881</ref> | {{SGDpaper|S000070226}} PMID 12052881</ref> | ||
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Revision as of 13:05, 3 June 2011
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Systematic name | YLR113W |
Gene name | HOG1 |
Aliases | SSK3 |
Feature type | ORF, Verified |
Coordinates | Chr XII:371620..372927 |
Primary SGDID | S000004103 |
Description of YLR113W: Mitogen-activated protein kinase involved in osmoregulation; acts via three independent osmosensors; mitophagy-specific regulator; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p[1][2][3][4][5]
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References
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- ↑ Alepuz PM, et al. (2003) Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II. EMBO J 22(10):2433-42 SGD PMID 12743037
- ↑ Brewster JL, et al. (1993) An osmosensing signal transduction pathway in yeast. Science 259(5102):1760-3 SGD PMID 7681220
- ↑ Mao K, et al. (2011) Two MAPK-signaling pathways are required for mitophagy in Saccharomyces cerevisiae. J Cell Biol 193(4):755-67 SGD PMID 21576396
- ↑ Mattison CP and Ota IM (2000) Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast. Genes Dev 14(10):1229-35 SGD PMID 10817757
- ↑ O'Rourke SM and Herskowitz I (2002) A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel with the Sho1 branch. Mol Cell Biol 22(13):4739-49 SGD PMID 12052881
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