Difference between revisions of "YKL191W"

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|nowrap| Chr XI:81040..82644
 
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==Community Commentary==
 
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==References==
 
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Revision as of 07:18, 30 January 2007

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Systematic name YKL191W
Gene name DPH2
Aliases
Feature type ORF, Verified
Coordinates Chr XI:81040..82644


Description of YKL191W: Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p[1][2][3]




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Community Commentary

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References

See Help:References on how to add references

  1. Liu S, et al. (2004) Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. Mol Cell Biol 24(21):9487-97 SGD PMID 15485916
  2. Fichtner L, et al. (2003) Elongator's toxin-target (TOT) function is nuclear localization sequence dependent and suppressed by post-translational modification. Mol Microbiol 49(5):1297-307 SGD PMID 12940988
  3. Mattheakis LC, et al. (1993) Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene. Gene 132(1):149-54 SGD PMID 8406038

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