Difference between revisions of "YMR116C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ASC1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ASC1 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''CPC2''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''CPC2, NAD1''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]

Revision as of 13:05, 24 March 2011

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Systematic name YMR116C
Gene name ASC1
Aliases CPC2, NAD1
Feature type ORF, Verified
Coordinates Chr XIII:500688..499456
Primary SGDID S000004722


Description of YMR116C: G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation[1][2][3][4]




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References

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  1. Chantrel Y, et al. (1998) The transcriptional regulator Hap1p (Cyp1p) is essential for anaerobic or heme-deficient growth of Saccharomyces cerevisiae: Genetic and molecular characterization of an extragenic suppressor that encodes a WD repeat protein. Genetics 148(2):559-69 SGD PMID 9504906
  2. Gerbasi VR, et al. (2004) Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression. Mol Cell Biol 24(18):8276-87 SGD PMID 15340087
  3. Hoffmann B, et al. (1999) The WD protein Cpc2p is required for repression of Gcn4 protein activity in yeast in the absence of amino-acid starvation. Mol Microbiol 31(3):807-22 SGD PMID 10048025
  4. Zeller CE, et al. (2007) The RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast. J Biol Chem 282(34):25168-76 SGD PMID 17591772

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