Difference between revisions of "YDR411C"

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'''Description of YDR411C:''' ER localized derlin-like family member involved in ER stress and homeostasis; not involved in ERAD or substrate retrotranslocation; interacts with CDC48; contains four transmembrane domains and two SHP boxes<ref name='S000076178'>Hitt R and Wolf DH (2004) Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins. FEMS Yeast Res 4(7):721-9 {{SGDpaper|S000076178}} PMID 15093775</ref><ref name='S000119480'>Sato BK and Hampton RY (2006) Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis. Yeast 23(14-15):1053-64
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'''Description of YDR411C:''' Endoplasmic reticulum (ER) localized protein involved in ER-associated protein degradation (ERAD), ER stress and homeostasis; interacts with components of ERAD-L and ERAD-C and Cdc48p; derlin-like family member similar to Der1p<ref name='S000076178'>Hitt R and Wolf DH (2004) Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins. FEMS Yeast Res 4(7):721-9 {{SGDpaper|S000076178}} PMID 15093775</ref><ref name='S000119480'>Sato BK and Hampton RY (2006) Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis. Yeast 23(14-15):1053-64 {{SGDpaper|S000119480}} PMID 17083136</ref><ref name='S000144378'>Stolz A, et al. (2010) Dfm1 forms distinct complexes with Cdc48 and the ER ubiquitin ligases and is required for ERAD. Traffic 11(10):1363-9
  {{SGDpaper|S000119480}} PMID 17083136</ref>
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  {{SGDpaper|S000144378}} PMID 20579315</ref>
 
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Revision as of 13:05, 17 February 2011

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Systematic name YDR411C
Gene name DFM1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1294394..1293369
Primary SGDID S000002819


Description of YDR411C: Endoplasmic reticulum (ER) localized protein involved in ER-associated protein degradation (ERAD), ER stress and homeostasis; interacts with components of ERAD-L and ERAD-C and Cdc48p; derlin-like family member similar to Der1p[1][2][3]




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References

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  1. Hitt R and Wolf DH (2004) Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins. FEMS Yeast Res 4(7):721-9 SGD PMID 15093775
  2. Sato BK and Hampton RY (2006) Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis. Yeast 23(14-15):1053-64 SGD PMID 17083136
  3. Stolz A, et al. (2010) Dfm1 forms distinct complexes with Cdc48 and the ER ubiquitin ligases and is required for ERAD. Traffic 11(10):1363-9 SGD PMID 20579315

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