Difference between revisions of "YLR220W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:576827..577795
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|nowrap| Chr XII:576825..577793
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004210
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004210

Revision as of 14:05, 3 February 2011

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Systematic name YLR220W
Gene name CCC1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:576825..577793
Primary SGDID S000004210


Description of YLR220W: Putative vacuolar Fe2+/Mn2+ transporter; suppresses respiratory deficit of yfh1 mutants, which lack the ortholog of mammalian frataxin, by preventing mitochondrial iron accumulation[1][2][3]




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References

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  1. Chen OS and Kaplan J (2000) CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation. J Biol Chem 275(11):7626-32 SGD PMID 10713071
  2. Lapinskas PJ, et al. (1996) The role of the Saccharomyces cerevisiae CCC1 gene in the homeostasis of manganese ions. Mol Microbiol 21(3):519-28 SGD PMID 8866476
  3. Li L, et al. (2001) CCC1 is a transporter that mediates vacuolar iron storage in yeast. J Biol Chem 276(31):29515-9 SGD PMID 11390404

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