Difference between revisions of "YJR070C"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr X: | + | |nowrap| Chr X:570598..569621 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003831 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003831 |
Revision as of 14:05, 3 February 2011
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Systematic name | YJR070C |
Gene name | LIA1 |
Aliases | MMD1 |
Feature type | ORF, Verified |
Coordinates | Chr X:570598..569621 |
Primary SGDID | S000003831 |
Description of YJR070C: Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyzes hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning[1][2][3]
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References
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- ↑ Park JH, et al. (2006) Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: a HEAT-repeat-containing metalloenzyme. Proc Natl Acad Sci U S A 103(1):51-6 SGD PMID 16371467
- ↑ Thompson GM, et al. (2003) Mapping eIF5A binding sites for Dys1 and Lia1: in vivo evidence for regulation of eIF5A hypusination. FEBS Lett 555(3):464-8 SGD PMID 14675757
- ↑ Weir BA and Yaffe MP (2004) Mmd1p, a novel, conserved protein essential for normal mitochondrial morphology and distribution in the fission yeast Schizosaccharomyces pombe. Mol Biol Cell 15(4):1656-65 SGD PMID 14767070
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