Difference between revisions of "YDR075W"

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|nowrap| Chr IV:597153..598079
 
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==Community Commentary==
 
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==References==
 
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Revision as of 07:17, 30 January 2007

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Systematic name YDR075W
Gene name PPH3
Aliases
Feature type ORF, Verified
Coordinates Chr IV:597153..598079


Description of YDR075W: Catalytic subunit of an evolutionarily conserved protein phosphatase complex containing Psy2p and the regulatory subunit Psy4p; required for cisplatin resistance; involved in activation of Gln3p[1][2][3]




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Community Commentary

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References

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  1. Hastie CJ, et al. (2006) The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin. FEBS J 273(14):3322-34 SGD PMID 16857015
  2. Hoffmann R, et al. (1994) The Saccharomyces cerevisiae gene PPH3 encodes a protein phosphatase with properties different from PPX, PP1 and PP2A. Yeast 10(5):567-78 SGD PMID 7941742
  3. Bertram PG, et al. (2000) Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases. J Biol Chem 275(46):35727-33 SGD PMID 10940301

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