Difference between revisions of "YGL246C"
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− | '''Description of YGL246C:''' Nuclear protein | + | '''Description of YGL246C:''' Nuclear protein with decapping endonuclease activity targeted toward mRNAs with unmethylated 7-methylguanosine cap structures; binds to and stabilizes the exoribonuclease Rat1p; required for pre-rRNA processing; homologous to human DOM3Z<ref name='S000136242'>Jiao X, et al. (2010) Identification of a quality-control mechanism for mRNA 5'-end capping. Nature 467(7315):608-11 {{SGDpaper|S000136242}} PMID 20802481</ref><ref name='S000072983'>Sydorskyy Y, et al. (2003) Intersection of the Kap123p-mediated nuclear import and ribosome export pathways. Mol Cell Biol 23(6):2042-54 {{SGDpaper|S000072983}} PMID 12612077</ref><ref name='S000043334'>Xue Y, et al. (2000) Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. Mol Cell Biol 20(11):4006-15 |
{{SGDpaper|S000043334}} PMID 10805743</ref> | {{SGDpaper|S000043334}} PMID 10805743</ref> | ||
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Revision as of 14:05, 14 December 2010
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Systematic name | YGL246C |
Gene name | RAI1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:38780..37617 |
Primary SGDID | S000003215 |
Description of YGL246C: Nuclear protein with decapping endonuclease activity targeted toward mRNAs with unmethylated 7-methylguanosine cap structures; binds to and stabilizes the exoribonuclease Rat1p; required for pre-rRNA processing; homologous to human DOM3Z[1][2][3]
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References
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- ↑ Jiao X, et al. (2010) Identification of a quality-control mechanism for mRNA 5'-end capping. Nature 467(7315):608-11 SGD PMID 20802481
- ↑ Sydorskyy Y, et al. (2003) Intersection of the Kap123p-mediated nuclear import and ribosome export pathways. Mol Cell Biol 23(6):2042-54 SGD PMID 12612077
- ↑ Xue Y, et al. (2000) Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. Mol Cell Biol 20(11):4006-15 SGD PMID 10805743
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