Difference between revisions of "YDR063W"
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| − | '''Description of YDR063W:''' | + | '''Description of YDR063W:''' Protein that interacts with Arp2/3 complex to stimulate actin filament debranching and inhibit actin nucleation; has similarity to Cof1p and also to human glia maturation factor (GMF); null mutant displays elevated mitochondrial genome loss<ref name='S000133660'>Gandhi M, et al. (2010) GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol 20(9):861-7 {{SGDpaper|S000133660}} PMID 20362448</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 {{SGDpaper|S000071347}} PMID 12140549</ref><ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 |
{{SGDpaper|S000074185}} PMID 14562095</ref> | {{SGDpaper|S000074185}} PMID 14562095</ref> | ||
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Revision as of 13:05, 20 July 2010
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| Systematic name | YDR063W |
| Gene name | AIM7 |
| Aliases | GMF, GMF1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:578662..579111 |
| Primary SGDID | S000002470 |
Description of YDR063W: Protein that interacts with Arp2/3 complex to stimulate actin filament debranching and inhibit actin nucleation; has similarity to Cof1p and also to human glia maturation factor (GMF); null mutant displays elevated mitochondrial genome loss[1][2][3][4]
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References
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- ↑ Gandhi M, et al. (2010) GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol 20(9):861-7 SGD PMID 20362448
- ↑ Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
- ↑ Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 SGD PMID 19300474
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
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