Difference between revisions of "YLR336C"
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| − | '''Description of YLR336C:''' Essential nuclear protein | + | '''Description of YLR336C:''' Essential nuclear protein, required for biogenesis of the small ribosomal subunit; has a possible role in the osmoregulatory glycerol response; putative homolog of human NOM1 which is implicated in acute myeloid leukemia<ref name='S000059303'>Akhtar N, et al. (2000) SGD1 encodes an essential nuclear protein of Saccharomyces cerevisiae that affects expression of the GPD1 gene for glycerol 3-phosphate dehydrogenase. FEBS Lett 483(2-3):87-92 {{SGDpaper|S000059303}} PMID 11042259</ref><ref name='S000131880'>Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 {{SGDpaper|S000131880}} PMID 19806183</ref><ref name='S000070006'>Lin H, et al. (2002) Phospholipase C interacts with Sgd1p and is required for expression of GPD1 and osmoresistance in Saccharomyces cerevisiae. Mol Genet Genomics 267(3):313-20 {{SGDpaper|S000070006}} PMID 12073033</ref><ref name='S000080799'>Simmons HM, et al. (2005) Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. Gene 347(1):137-45 |
{{SGDpaper|S000080799}} PMID 15715967</ref> | {{SGDpaper|S000080799}} PMID 15715967</ref> | ||
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Revision as of 13:05, 3 May 2010
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| Systematic name | YLR336C |
| Gene name | SGD1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:802396..799697 |
| Primary SGDID | S000004328 |
Description of YLR336C: Essential nuclear protein, required for biogenesis of the small ribosomal subunit; has a possible role in the osmoregulatory glycerol response; putative homolog of human NOM1 which is implicated in acute myeloid leukemia[1][2][3][4]
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References
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- ↑ Akhtar N, et al. (2000) SGD1 encodes an essential nuclear protein of Saccharomyces cerevisiae that affects expression of the GPD1 gene for glycerol 3-phosphate dehydrogenase. FEBS Lett 483(2-3):87-92 SGD PMID 11042259
- ↑ Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 SGD PMID 19806183
- ↑ Lin H, et al. (2002) Phospholipase C interacts with Sgd1p and is required for expression of GPD1 and osmoresistance in Saccharomyces cerevisiae. Mol Genet Genomics 267(3):313-20 SGD PMID 12073033
- ↑ Simmons HM, et al. (2005) Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. Gene 347(1):137-45 SGD PMID 15715967
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