Difference between revisions of "YHL007C"
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| − | '''Description of YHL007C:''' Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family | + | '''Description of YHL007C:''' Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p<ref name='S000129348'>Bartholomew CR and Hardy CF (2009) p21-activated kinases Cla4 and Ste20 regulate vacuole inheritance in Saccharomyces cerevisiae. Eukaryot Cell 8(4):560-72 {{SGDpaper|S000129348}} PMID 19218422</ref><ref name='S000131819'>Lin M, et al. (2009) The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway. Mol Biol Cell 20(22):4826-37 {{SGDpaper|S000131819}} PMID 19793923</ref><ref name='S000044194'>Peter M, et al. (1996) Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast. EMBO J 15(24):7046-59 {{SGDpaper|S000044194}} PMID 9003780</ref><ref name='S000066166'>Song J, et al. (2001) Molecular interactions of the Gbeta binding domain of the Ste20p/PAK family of protein kinases. An isolated but fully functional Gbeta binding domain from Ste20p is only partially folded as shown by heteronuclear NMR spectroscopy. J Biol Chem 276(44):41205-12 |
{{SGDpaper|S000066166}} PMID 11509560</ref> | {{SGDpaper|S000066166}} PMID 11509560</ref> | ||
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Revision as of 13:05, 30 March 2010
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| Systematic name | YHL007C |
| Gene name | STE20 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:97933..95114 |
| Primary SGDID | S000000999 |
Description of YHL007C: Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p[1][2][3][4]
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References
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- ↑ Bartholomew CR and Hardy CF (2009) p21-activated kinases Cla4 and Ste20 regulate vacuole inheritance in Saccharomyces cerevisiae. Eukaryot Cell 8(4):560-72 SGD PMID 19218422
- ↑ Lin M, et al. (2009) The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway. Mol Biol Cell 20(22):4826-37 SGD PMID 19793923
- ↑ Peter M, et al. (1996) Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast. EMBO J 15(24):7046-59 SGD PMID 9003780
- ↑ Song J, et al. (2001) Molecular interactions of the Gbeta binding domain of the Ste20p/PAK family of protein kinases. An isolated but fully functional Gbeta binding domain from Ste20p is only partially folded as shown by heteronuclear NMR spectroscopy. J Biol Chem 276(44):41205-12 SGD PMID 11509560
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