Difference between revisions of "YPR019W"
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| − | '''Description of YPR019W:''' Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p | + | '''Description of YPR019W:''' Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p<ref name='S000069529'>Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207 {{SGDpaper|S000069529}} PMID 11836525</ref><ref name='S000042473'>Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68:649-86 |
| − | {{SGDpaper| | + | {{SGDpaper|S000042473}} PMID 10872463</ref> |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YPR019W |
| Gene name | MCM4 |
| Aliases | CDC54, HCD21 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:596747..599548 |
| Primary SGDID | S000006223 |
Description of YPR019W: Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p[1][2]
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