Difference between revisions of "YPL061W"

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'''Description of YPL061W:''' Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress<ref name='S000039810'>Navarro-Avino JP, et al. (1999) A proposal for nomenclature of aldehyde dehydrogenases in Saccharomyces cerevisiae and characterization of the stress-inducible ALD2 and ALD3 genes. Yeast 15(10A):829-42 {{SGDpaper|S000039810}} PMID 10407263</ref><ref name='S000076746'>Saint-Prix F, et al. (2004) Functional analysis of the ALD gene family of Saccharomyces cerevisiae during anaerobic growth on glucose: the NADP+-dependent Ald6p and Ald5p isoforms play a major role in acetate formation. Microbiology 150(Pt 7):2209-20 {{SGDpaper|S000076746}} PMID 15256563</ref><ref name='S000116817'>Rinnerthaler M, et al. (2006) MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria. Biochim Biophys Acta 1757(5-6):631-8
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'''Description of YPL061W:''' Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress<ref name='S000039810'>Navarro-Avino JP, et al. (1999) A proposal for nomenclature of aldehyde dehydrogenases in Saccharomyces cerevisiae and characterization of the stress-inducible ALD2 and ALD3 genes. Yeast 15(10A):829-42 {{SGDpaper|S000039810}} PMID 10407263</ref><ref name='S000116817'>Rinnerthaler M, et al. (2006) MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria. Biochim Biophys Acta 1757(5-6):631-8 {{SGDpaper|S000116817}} PMID 16806052</ref><ref name='S000076746'>Saint-Prix F, et al. (2004) Functional analysis of the ALD gene family of Saccharomyces cerevisiae during anaerobic growth on glucose: the NADP+-dependent Ald6p and Ald5p isoforms play a major role in acetate formation. Microbiology 150(Pt 7):2209-20
{{SGDpaper|S000116817}} PMID 16806052</ref>
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{{SGDpaper|S000076746}} PMID 15256563</ref>
 
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Revision as of 13:05, 25 February 2010

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Systematic name YPL061W
Gene name ALD6
Aliases ALD1
Feature type ORF, Verified
Coordinates Chr XVI:432585..434087
Primary SGDID S000005982


Description of YPL061W: Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress[1][2][3]




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References

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  1. Navarro-Avino JP, et al. (1999) A proposal for nomenclature of aldehyde dehydrogenases in Saccharomyces cerevisiae and characterization of the stress-inducible ALD2 and ALD3 genes. Yeast 15(10A):829-42 SGD PMID 10407263
  2. Rinnerthaler M, et al. (2006) MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria. Biochim Biophys Acta 1757(5-6):631-8 SGD PMID 16806052
  3. Saint-Prix F, et al. (2004) Functional analysis of the ALD gene family of Saccharomyces cerevisiae during anaerobic growth on glucose: the NADP+-dependent Ald6p and Ald5p isoforms play a major role in acetate formation. Microbiology 150(Pt 7):2209-20 SGD PMID 15256563

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