Difference between revisions of "YPL006W"

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'''Description of YPL006W:''' Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein<ref name='S000080257'>Zhang S, et al. (2004) Ncr1p, the yeast ortholog of mammalian Niemann Pick C1 protein, is dispensable for endocytic transport. Traffic 5(12):1017-30 {{SGDpaper|S000080257}} PMID 15522102</ref><ref name='S000075552'>Malathi K, et al. (2004) Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution. J Cell Biol 164(4):547-56
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'''Description of YPL006W:''' Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein<ref name='S000075552'>Malathi K, et al. (2004) Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution. J Cell Biol 164(4):547-56 {{SGDpaper|S000075552}} PMID 14970192</ref><ref name='S000080257'>Zhang S, et al. (2004) Ncr1p, the yeast ortholog of mammalian Niemann Pick C1 protein, is dispensable for endocytic transport. Traffic 5(12):1017-30
  {{SGDpaper|S000075552}} PMID 14970192</ref>
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  {{SGDpaper|S000080257}} PMID 15522102</ref>
 
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Revision as of 13:05, 25 February 2010

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Systematic name YPL006W
Gene name NCR1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:544628..548140
Primary SGDID S000005927


Description of YPL006W: Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein[1][2]




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References

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  1. Malathi K, et al. (2004) Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution. J Cell Biol 164(4):547-56 SGD PMID 14970192
  2. Zhang S, et al. (2004) Ncr1p, the yeast ortholog of mammalian Niemann Pick C1 protein, is dispensable for endocytic transport. Traffic 5(12):1017-30 SGD PMID 15522102

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