Difference between revisions of "YNL082W"
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| − | '''Description of YNL082W:''' ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL | + | '''Description of YNL082W:''' ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL<ref name='S000069240'>Hall MC, et al. (2002) Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins. J Biol Chem 277(5):3673-9 {{SGDpaper|S000069240}} PMID 11717305</ref><ref name='S000078165'>Hall MC, et al. (2003) DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair. Nucleic Acids Res 31(8):2025-34 {{SGDpaper|S000078165}} PMID 12682353</ref><ref name='S000040150'>Williamson MS, et al. (1985) Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2. Genetics 110(4):609-46 |
| − | {{SGDpaper| | + | {{SGDpaper|S000040150}} PMID 3896926</ref> |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YNL082W |
| Gene name | PMS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:473393..476014 |
| Primary SGDID | S000005026 |
Description of YNL082W: ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL[1][2][3]
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References
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- ↑ Hall MC, et al. (2002) Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins. J Biol Chem 277(5):3673-9 SGD PMID 11717305
- ↑ Hall MC, et al. (2003) DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair. Nucleic Acids Res 31(8):2025-34 SGD PMID 12682353
- ↑ Williamson MS, et al. (1985) Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2. Genetics 110(4):609-46 SGD PMID 3896926
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