Difference between revisions of "YLR103C"
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| − | '''Description of YLR103C:''' DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes | + | '''Description of YLR103C:''' DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes<ref name='S000074822'>McKie JM, et al. (1998) Direct selection of conserved cDNAs from the DiGeorge critical region: isolation of a novel CDC45-like gene. Genome Res 8(8):834-41 {{SGDpaper|S000074822}} PMID 9724329</ref><ref name='S000042473'>Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68:649-86 |
| − | {{SGDpaper| | + | {{SGDpaper|S000042473}} PMID 10872463</ref> |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YLR103C |
| Gene name | CDC45 |
| Aliases | SLD4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:345942..343990 |
| Primary SGDID | S000004093 |
Description of YLR103C: DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes[1][2]
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