Difference between revisions of "YGR277C"
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| − | '''Description of YGR277C:''' Probable pantetheine-phosphate adenylyltransferase (PPAT), which catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate; null mutant lethality is complemented by E. coli coaD (encoding PPAT); widely conserved<ref name=' | + | '''Description of YGR277C:''' Probable pantetheine-phosphate adenylyltransferase (PPAT), which catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate; null mutant lethality is complemented by E. coli coaD (encoding PPAT); widely conserved<ref name='S000073342'>Daugherty M, et al. (2002) Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics. J Biol Chem 277(24):21431-9 {{SGDpaper|S000073342}} PMID 11923312</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 {{SGDpaper|S000071347}} PMID 12140549</ref><ref name='S000129524'>Olzhausen J, et al. (2009) Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1. Curr Genet 55(2):163-73 |
{{SGDpaper|S000129524}} PMID 19266201</ref> | {{SGDpaper|S000129524}} PMID 19266201</ref> | ||
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Revision as of 14:05, 25 February 2010
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| Systematic name | YGR277C |
| Gene name | CAB4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:1046568..1045651 |
| Primary SGDID | S000003509 |
Description of YGR277C: Probable pantetheine-phosphate adenylyltransferase (PPAT), which catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate; null mutant lethality is complemented by E. coli coaD (encoding PPAT); widely conserved[1][2][3]
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References
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- ↑ Daugherty M, et al. (2002) Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics. J Biol Chem 277(24):21431-9 SGD PMID 11923312
- ↑ Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
- ↑ Olzhausen J, et al. (2009) Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1. Curr Genet 55(2):163-73 SGD PMID 19266201
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