Difference between revisions of "YGL231C"
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| − | '''Description of YGL231C:''' Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; human ortholog TMEM85 may function in apoptosis<ref name=' | + | '''Description of YGL231C:''' Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; human ortholog TMEM85 may function in apoptosis<ref name='S000129738'>Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7 {{SGDpaper|S000129738}} PMID 19325107</ref><ref name='S000126913'>Ring G, et al. (2008) Transmembrane protein 85 from both human (TMEM85) and yeast (YGL231c) inhibit hydrogen peroxide mediated cell death in yeast. FEBS Lett 582(17):2637-42 |
| − | {{SGDpaper| | + | {{SGDpaper|S000126913}} PMID 18586032</ref> |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YGL231C |
| Gene name | EMC4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:63620..63048 |
| Primary SGDID | S000003200 |
Description of YGL231C: Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; human ortholog TMEM85 may function in apoptosis[1][2]
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References
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- ↑ Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7 SGD PMID 19325107
- ↑ Ring G, et al. (2008) Transmembrane protein 85 from both human (TMEM85) and yeast (YGL231c) inhibit hydrogen peroxide mediated cell death in yeast. FEBS Lett 582(17):2637-42 SGD PMID 18586032
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