Difference between revisions of "YDR014W"

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'''Description of YDR014W:''' Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin<ref name='S000127161'>Ben-Shahar TR, et al. (2008) Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321(5888):563-6 {{SGDpaper|S000127161}} PMID 18653893</ref><ref name='S000127217'>Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127(5):955-67 {{SGDpaper|S000127217}} PMID 17113138</ref><ref name='S000129631'>Sutani T, et al. (2009) Budding yeast Wpl1(Rad61)-Pds5 complex counteracts sister chromatid cohesion-establishing reaction. Curr Biol 19(6):492-7 {{SGDpaper|S000129631}} PMID 19268589</ref><ref name='S000129839'>Rowland BD, et al. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell 33(6):763-74
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'''Description of YDR014W:''' Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin<ref name='S000127161'>Ben-Shahar TR, et al. (2008) Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321(5888):563-6 {{SGDpaper|S000127161}} PMID 18653893</ref><ref name='S000127217'>Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127(5):955-67 {{SGDpaper|S000127217}} PMID 17113138</ref><ref name='S000129839'>Rowland BD, et al. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell 33(6):763-74 {{SGDpaper|S000129839}} PMID 19328069</ref><ref name='S000129631'>Sutani T, et al. (2009) Budding yeast Wpl1(Rad61)-Pds5 complex counteracts sister chromatid cohesion-establishing reaction. Curr Biol 19(6):492-7
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  {{SGDpaper|S000129631}} PMID 19268589</ref>
 
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Revision as of 13:05, 25 February 2010

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Systematic name YDR014W
Gene name RAD61
Aliases WPL1
Feature type ORF, Verified
Coordinates Chr IV:474044..475987
Primary SGDID S000002421


Description of YDR014W: Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin[1][2][3][4]




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References

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  1. Ben-Shahar TR, et al. (2008) Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321(5888):563-6 SGD PMID 18653893
  2. Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127(5):955-67 SGD PMID 17113138
  3. Rowland BD, et al. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell 33(6):763-74 SGD PMID 19328069
  4. Sutani T, et al. (2009) Budding yeast Wpl1(Rad61)-Pds5 complex counteracts sister chromatid cohesion-establishing reaction. Curr Biol 19(6):492-7 SGD PMID 19268589

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