Difference between revisions of "YKR007W"

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'''Description of YKR007W:''' Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; loss results in a defect in vacuolar acidification<ref name='S000116213'>Gao M and Kaiser CA (2006) A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat Cell Biol 8(7):657-67 {{SGDpaper|S000116213}} PMID 16732272</ref><ref name='S000081946'>Gao XD, et al. (2005) ERS1 encodes a functional homologue of the human lysosomal cystine transporter. FEBS J 272(10):2497-511 {{SGDpaper|S000081946}} PMID 15885099</ref><ref name='S000082228'>Dubouloz F, et al. (2005) The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 19(1):15-26
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'''Description of YKR007W:''' Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; loss results in a defect in vacuolar acidification<ref name='S000082228'>Dubouloz F, et al. (2005) The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 19(1):15-26 {{SGDpaper|S000082228}} PMID 15989961</ref><ref name='S000116213'>Gao M and Kaiser CA (2006) A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat Cell Biol 8(7):657-67 {{SGDpaper|S000116213}} PMID 16732272</ref><ref name='S000081946'>Gao XD, et al. (2005) ERS1 encodes a functional homologue of the human lysosomal cystine transporter. FEBS J 272(10):2497-511
{{SGDpaper|S000082228}} PMID 15989961</ref>
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{{SGDpaper|S000081946}} PMID 15885099</ref>
 
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Revision as of 13:05, 25 February 2010

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Systematic name YKR007W
Gene name MEH1
Aliases EGO1, GSE2
Feature type ORF, Verified
Coordinates Chr XI:451077..451631
Primary SGDID S000001715


Description of YKR007W: Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; loss results in a defect in vacuolar acidification[1][2][3]




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References

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  1. Dubouloz F, et al. (2005) The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 19(1):15-26 SGD PMID 15989961
  2. Gao M and Kaiser CA (2006) A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat Cell Biol 8(7):657-67 SGD PMID 16732272
  3. Gao XD, et al. (2005) ERS1 encodes a functional homologue of the human lysosomal cystine transporter. FEBS J 272(10):2497-511 SGD PMID 15885099

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